Nocturnal Leg Cramps and Prescription Use

Cramp treatment was substantially more likely in the year following introduction of LABAs, potassium-sparing diuretics, or thiazidelike diuretics, and 60.3% of quinine users (individuals experiencing cramp) received at least 1 of these medications during a 13-year period. In contrast, statin and loop diuretic associations were small. Physicians should be mindful that the use of these medications may worsen symptoms in patients experiencing nocturnal leg cramps

Zdroj:

Arch Intern Med -- Abstract: Nocturnal Leg Cramps and Prescription Use That Precedes Them: A Sequence Symmetry Analysis, January 23, 2012, Garrison et al. 172 (2): 120